Edit Distance
Given two protein or DNA strings, compute their edit distance: the minimum number of insertions, deletions and substitutions required to …
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Computational Biology
Algorithms and models: dynamic-programming alignment, phylogenetics and hidden Markov models.
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Showing 1–4 of 4 problems
Merge Overlapping Exon Intervals
You are given a set of exon intervals as half-open ranges [start, end) on a single chromosome. Merge every group …
Hardy-Weinberg Equilibrium Test
You are given the observed counts of three genotypes at a biallelic locus: homozygous for the major allele (AA), heterozygous …
CPM Normalisation of a Count Matrix
You are given a gene expression count matrix. The first line is a header with the gene column label followed …
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